We mark the death of the violinistic wizard, composer, and showman extraordinaire Niccolò Paganini, who died 179 years ago today in the Mediterranean resort city of Nice on May 27, 1840. Marfan Syndrome (or “MFS”) is a genetic disorder of the connective tissue. The syndrome is named after the French pediatrician Antoine Marfan, who first identified it in 1891. For those – like me – who must know, the gene linked to the condition was identified in 1991 by Francesco Ramirez at New York City’s Mount Sinai Medical Center. Folks with Marfan Syndrome are characteristically tall and slim; with long arms, legs, fingers and toes. Their joints are typically flexible; sometime crazy flexible, the sort of crazy flexible that makes the rest of us squirm with discomfort when we see such a person casually twist him or herself up like a human pretzel. Marfan Syndrome can affect the heart as well, and thus the American Heart Association, ever the Helpy Helperton, has made recommendations regarding the sorts of activities folks with Marfan can and should not engage in.  The American Heart Association lists as “high risk” activities for Marfan sufferers bodybuilding, weightlifting (non-free and free weights), ice hockey, rock climbing, […]